Metal Gear Survive is a co-op zombie survival game set in the Metal Gear franchise. Set in 1975 during the ending of Metal Gear Solid V: Ground Zeroes, as Big Boss and Kazuhira Miller escape the destruction the original Mother Base (of Metal Gear Solid: Peace Walker fame) at the hands of XOF forces, a handful of survivors are swept into a wormhole above the offshore facility into an alternate dimension. There the survivors must fight crystalline zombies to find a way back home. The story is set in a separate timeline from the events of Ground Zeros and the core Metal Gear franchise.
Much of the gameplay revolves around base-building and management, including finding new survivors, ensuring that they have shelter, food, and water, and maintaining your main character's own personal hunger, thirst, and oxygen levels.
The game's multiplayer mode consists of four-player wave-based survival missions, all of which have players defending an energy mining device from incoming zombies. Some of these missions also appear in the game's single-player component as part of the story progression.